Biological signaling by small inorganic molecules

Small Molecules and Biological Activities

The chemical and bioactivity resources at the National Center for Biotechnology Information (NCBI) are coordinated as part of the PubChem Project with data accessible as part of the PubChem Compound and Substance databases and PubChem BioAssay database, respectively. Currently the PubChem set of resources provides access to information about over 36 million chemical compounds and experimental s...

Crystallography of Biological Small Molecules

C278 P.05.08.4 Acta Cryst. (2005). A61, C278 Synthesis and Structural Characterization of 3-(4-fluorophenyl)2-( -naphtyl)-1,3-thiazolidin-4-one José Luis Pinto Camargo, J. A. Henao, W. Rodríguez, V. V. Kouznetsov, Grupo de Investigación en Química Estructural, Centro de Investigación en Biomoléculas “CIBIMOL”, Escuela de Química, Facultad de Ciencias, Universidad Industrial de Santander, A. A. ...

Biological signaling by carbon monoxide and carbon monoxide-releasing molecules.

Carbon monoxide (CO) is continuously produced in mammalian cells during the degradation of heme. It is a stable gaseous molecule that reacts selectively with transition metals in a specific redox state, and these characteristics restrict the interaction of CO with defined biological targets that transduce its signaling activity. Because of the high affinity of CO for ferrous heme, these targets...

Layer-by-layer self-assembly and disassembly of single charged inorganic small molecules: towards surface patterning.

The patterning of layer-by-layer (LbL) polyelectrolyte multilayers with metal ions is important for the facile fabrication of circuits or selective catalysis. The strategy includes two issues: the incorporation of metal ions and their controlled assembly-disassembly, which require a good understanding of the assembly mechanism. Therefore, we explored the LbL assembly between a polycation, poly-...

INTERACTION OF PROTEINS WITH SMALL MOLECULES